Life Science

POVACOAT Pharmaceutical excipient for oral preparations

Pharmaceutical excipient for oral preparations POVACOAT® was listed as a Japanese Pharmaceutical Excipient (JPE) in December 2012. In terms of chemical structure, it is a synthetic polymer produced by the copolymerization of partially-saponified polyvinyl alcohol with acrylic acid and methyl methacrylate. POVACOAT offers a dense and strong film structure and is used in film coatings to add oxygen barrier effects and moisture-resistance. It also serves as a high-performance binder that offers high binding strength and reduces problems in tablet manufacturing.
(Listed as a Japanese Pharmaceutical Excipient (JPE) in December 2012.)

Structural formula

Structural formula
Generic name PVA copolymer
Drug name Copolymer of polyvinyl alcohol, acrylic acid and methyl methacrylate
Drug Master File Registered
Precedent use 72 mg per day (Administration: oral)

POVACOAT product lineup

Type F MP FL (Under development)
Properties (Appearance) White to yellowish-white lump or powder White to yellowish-white powder Slightly yellow, transparent liquid 
Specifications JPE JPE To be discussed
Viscosity (mPa•s) (For reference) 5.5 5.5 5.5
Average molecular weight Approx. 40,000 Approx. 40,000 Approx. 40,000
Average particle diameter Approx. 1.5 mm Approx. 125μm


Applications Film coating, wet granulation binder Wet granulation binders, solid dispersion substrates Wet granulation binders for film coatings

Contact us for our microparticle version of POVACOAT (developed upon request).

Application examples and technical materialsはこちら


  • Chemicals
  • Life Science
  • 成形品事業
tel:06-6471-7758 〒555-0011
  • お問い合わせ
  • 採用情報